Retro Dr. Mario Game Series Collection

Dr. Mario is a puzzle game where players assume the role of Mario as a doctor who must eliminate viruses by matching colored vitamin capsules. The game features infectious music and increasing difficulty levels that provide lasting challenge.

A combo cartridge featuring two classic Nintendo puzzle games: Dr. Mario's virus-busting action and Panel de Pon's tile-matching gameplay (rebranded as Puzzle League outside Japan).

The first 3D installment in the classic puzzle series, featuring enhanced multiplayer modes and new virus-busting mechanics. Players stack and match colored pills to eliminate viruses, now with four-player battles and special attack items.